产品货号：
Z27359
中文名称：
ST13抗体
英文名称：
Anti-ST13 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ST13 Antibody |
| 指标别名 | AAG2;FAM10A1;FAM10A4;HIP;HOP;Hsc70 interacting protein;HSPABP;HSPABP1;P48;PRO0786;Protein FAM10A1;Putative tumor suppressor ST13;SNC6;ST13 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,ICC/IF |
| 基因名称 | ST13 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human ST13(1-19aa MDPRKVNELRAFVKMCKQD),different from the related rat and mouse sequences by two amino acids. |
| 计算分子量 | 41KD |
| 实际分子量 | 45～54KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ST13(Suppression of Tumorigenicity 13),also known as P48 or HIP,is a protein that in humans is encoded by the ST13 gene.ST13 is an abundant,highly conserved protein that binds the major cytosolic chaperones heat-shock protein 70-kD(HSP70) and HSP90 during an intermediate stage of steroid receptor assembly,but is absent from the mature receptor complex.Zhang et al.(1998) mapped the ST13 gene to chromosome 22q13 by fluorescence in situ hybridization.They noted that colorectal,breast,and ovarian carcinomas frequently show loss of heterozygosity at this site.Using a yeast 2-hybrid assay,Hohfeld et al.(1995) showed that rat Hip bound Hsc70(HSPA8).One Hip oligomer bound the ATPase domains of at least 2 Hsc70 molecules,and binding was dependent on activation of the Hsc70 ATPase by Hsp40(DNAJB1).Hip stabilized the ADP-bound form of Hsc70,which had a high affinity for a test protein substrate.Hohfeld et al.(1995) concluded that HIP contributes to interactions of HSC70 with target proteins through its own chaperone activity. |
| Uniprot ID | P50502 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | suppression of tumorigenicity 13(colon carcinoma)(Hsp70 interacting protein) |
| 蛋白名全称 | Hsc70-interacting protein |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 |
相关搜索：ST13抗体，ST13多抗，Anti-ST13 Antibody